Study (Year) n (F), mean age (years) Diagnostic criteria Tendon involved (%) Activity level Average duration of symptoms (range)
RCTs
Cacchio (2011) 40 (13F), SWT 24 years, multi-modal intervention 24 years At least 2 of the following painful; Puranen Orava test, fast hamstring-stretch test, hamstring strength test
MRI
NR Multi-modal professional athletes: 40 Multi-modal intervention: 21 months (13-81)
SWT: 19.6 months (11-72)
Davenport (2015) 15 (13F), AWB: 45.4 years, PRP 47 years, 17 cases (2 bilateral) Clinical diagnosisa
Positive MRI or US
NR NR NR
Case series
Benazzo (2013) 17 (5F), 27 years Reporting pain at ischial tuberosity
Pain with concentric hamstring contraction: (positive 47%)
Tenderness ischial tuberosity (41% positive)
Puranen Orava test (88% positive)
Leg raising test (23% positive)
MRI
Bicep femoris (41%)
Semimembranosus (29%)
Semitendinosus (6%)
Common tendon (23%)*
Professional athletes: 9
Competitive athletes: 8
23 months (3-48)
Fader (2014) 18 (12F), 43 years Clinical diagnosisa
MRI
NR NR 32.6 months (6-120)
Krauss (2016) 14 (13F), 47 years At least 2 of the following;
Tenderness to palpation at ischial tuberosity, positive bent knee stretch test, positive supine plank test
MRI
NR NR 4.1 years (5 months to 10 years)
Lempainen (2009) 90 (32F), 34 years,
103 casesb (13 bilateral)
Patient interview and history
Pain at ischial tuberosity with hamstring stretch
MRI
All semimembranosus Professional: 5
Competitive: 47
Recreational: 38
NR
Levy (2019) 29 (22F), 45 years Clinical diagnosisa confirmed with positive MRI NR NR NR
Nicholson (2014) 18 (10F), 51 years, 22 cases (4 bilateral) Pain with prolonged sitting
Pain with hamstring contraction
MRI
NR Athletes: 18 28 months (2-120)
Puranen (1988) 59 (14F), Athletes: 25 years, joggers: 39 years, non-athletes: 35 years, 65 cases (6 bilateral) Pain on active stretching
Pain on palpation
NR Athletes: 50
Joggers: 4
Non-athletes: 5
NR
Wetzel (2012) 15 (8F), 38 years, 17 cases (2 bilateral) Clinical diagnosisa
MRI
NR PRP group:
Collegiate or high-level athletes: 9
NR: 1
Multi-modal intervention group:
High level athletes: 2
NR: 3
Multi-modal intervention: 7.8 months
PRP: 9.6 months
Young (2008) 44 (16F), 29 years, 47 cases (3 bilateral) Pain on palpation of proximal hamstring region
Weakness at 30ยบ of resisted knee flexion
MRI/US
NR Professional: 4
Semi-Professional: 7
Recreational: 33
8 cases: < 6 months
15 cases: 6-12 months
10 cases: 12-18 months
14 cases: >18 months
Zissen (2010) 65 (37F), 37.7 years Clinical diagnosisa
MRI/US
NR NR 8 cases: < 6months
15 cases: 6 months to 1 year
15 cases: > 1 year